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Table 4 Effect of AEVG on plasma lipoprotein profile and atherogenicity indices

From: Lipotropic activities of aqueous extract of Vernonia guineensis Benth. in Wistar rats fed high fat diet

Groups

TG

(mg/dL)

TC

(mg/dL)

HDL-c (mg/dL)

LDL-c

(mg/dL)

TC/HDL-c

LDL-c/ HDL-c

ND + distilled water (Normal Control)

63.62 ± 8.48a

25.88 ± 10.92a

3.85 ± 1.05

9.25 ± 1.58a

6.90 ± 3.20a

3.35 ± 3.27a

HFD + distilled water

(Negative Control)

98.77 ± 14.52b

62.68 ± 16.00b

2.56 ± 0.13

40.36 ± 17.15b

24.28 ± 5.35b

15.57 ± 6.23b

HFD + AEVG

(400 mg/kgBW)

59.75 ± 30.12a

35.00 ± 6.55a

4.25 ± 1.42a

19.32 ± 10.73a

9.63 ± 5.24a

5.70 ± 4.88a

HFD + Fenofibrate (100 mg/kgBW)

(Positive Control)

50.13 ± 8.06a

42.47 ± 13.47a

4.31 ± 0.66a

28.13 ± 14.60

9.78 ± 2.29a

6.43 ± 2.67a

  1. ND Normal diet, HFD high fat diet, AEVG aqueous extract of Vernonia guineensis, TG triglycerides, HDL-c high density lipoproteins cholesterol, LDL-c low density lipoproteins cholesterol
  2. Values were expressed as mean ± standard deviation
  3. an = 5 and bp < 0.05; significantly different compared to the negative control and the positive control respectively