Fig. 7

The effect of diosmin on PI3K/AKT/PTEN signal transduction in high glucose-mediated HK-2 cells. A-D. The effect of diosmin on phosphatidylinositol 3-kinase/protein kinase-B/ phosphatase and tensin homolog deleted on chromosome 10 pathway-related markers was detected by western blot. β-actin was used as a housekeeping gene. The results were expressed as the mean ± standard deviation (SD) of three independent experiments. Compared with the control group, ** p < 0.01. Compared with the high glucose group, # p < 0.05 and ## p < 0.01