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Fig. 2 | BMC Complementary Medicine and Therapies

Fig. 2

From: Trans-cinnamaldehyde protects against phenylephrine-induced cardiomyocyte hypertrophy through the CaMKII/ERK pathway

Fig. 2

The CaMKII-MEK-ERK signalling pathway was involved in PE-induced cardiac hypertrophy. A Representative immunoblots of CaMKII and GAPDH. B Quantification analysis of CaMKII. C Representative immunoblots of p-MEK, MEK, p-ERK, ERK and GAPDH. D Quantification analysis of MEK and ERK. E Representative confocal fluorescent images of α-actinin. Red: α-actinin; Blue: DAPI. F Analysis of cell surface area according to α-actinin immunofluorescence staining. *P < 0.05 versus control; #P < 0.05 versus PE. Naf: an α1-adrenergic receptor antagonist; 2-APB: an IP3 receptor antagonist; KN93: a CaMKII inhibitor; U0126: a MEK/ERK inhibitor

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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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