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Table 2 The major parameter of top 12 targets in PPI network of Eriocauli Flos and DR

From: The potential effects and mechanisms of hispidulin in the treatment of diabetic retinopathy based on network pharmacology

Target

Betweenness

Closeness

Degree

TP53

82.66727347

0.707317073

34

MAPK14

30.98526381

0.58

22

CCND1

43.52465867

0.617021277

24

MAPK1

69.96781552

0.617021277

26

AKT1

89.88644596

0.69047619

32

EGFR

51.27220002

0.617021277

24

EGF

30.91583787

0.557692308

16

FOS

16.80648241

0.604166667

20

MYC

21.58809431

0.630434783

24

VEGFA

81.02487512

0.630434783

24

TNF

46.13921264

0.58

24

JUN

78.67520165

0.69047619

32