Fig. 5

SBD inhibited PCa cell vitality and invasion target Akt. Cell viabilities of PC-3 (a) and DU145 (b) cell lines pre-treated by MK2206 were measured by CCK-8 assay after treatment with indicated concentrations of SBD. Cell invasion of PC-1 (c) and DU145 (d) cell lines that underwent SBD treatment was determined by transwell assay. Date was mean ± SEM (n = 4), p < 0.05 (*)