Fig. 3

Cipa principal bioactive compounds bind crucial SARS-CoV2 therapeutic targets. A represents molecular docking of Magnoflorine at the active site pocket of SARS-CoV2 3C-like protease. B represents molecular docking of Salutaridine with ACE2 interacting amino acid residues of Receptor Binding Domain (RBD) from SARS-Cov2 spike protein. The middle and the right panels of each figure represent the zoomed in view of the molecular interaction patterns of the docked ligands in three-dimensional and two-dimensional spaces respectively. In the two-dimensional interaction plots, the green dotted lines indicate hydrogen bond formation, whereas the hydrophobic interactions are represented by the spiked arcs