Fig. 4

HF induces apoptosis by activating JNK / p38 MAPK signaling pathway and inhibiting NF-κB activity in K562 cells. A, B Flow cytometry was used to analyze the apoptosis of K562 cells pre-treated with 10 μM SP600125 or 10 μM SB203580 for 1 h before exposed to 10 μM HF for 48 h. C, D The expression levels of proteins in K562 cells pre-treated with 10 μM SP600125 or 10 μM SB203580 for 1 h before exposed to 10 μM HF for 48 h. *P < 0.05, **P < 0.01, ***P < 0.001