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Table 1 Enriched GO terms in molecular functions (P < 0.05)

From: Parthenolide leads to proteomic differences in thyroid cancer cells and promotes apoptosis

ID

Description

GeneRatio

P-value

GO:0048037

cofactor binding

19|149

3.56E-08

GO:0051539

4 iron, 4 sulfur cluster binding

7|149

4.88E-08

GO:0051536

iron-sulfur cluster binding

8|149

6.62E-08

GO:0051540

metal cluster binding

8|149

6.62E-08

GO:0001618

virus receptor activity

7|149

3.09E-06

GO:0104005

hijacked molecular function

7|149

3.09E-06

GO:0008483

transaminase activity

4|149

2.67E-05

GO:0016779

nucleotidyltransferase activity

8|149

2.88E-05

GO:0016769

transferase activity, transferring nitrogenousgroups

4|149

3.90E-05

GO:0030350

iron-responsive element binding

2|149

7.16E-05

GO:0003887

DNA-directed DNA polymerase activity

4|149

0.000100511

GO:0016667

oxidoreductase activity, acting on a sulfur groupof donors

5|149

0.000167427

GO:0004748

ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor

2|149

0.000213652

GO:0016728

oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor

2|149

0.000213652

GO:0061731

ribonucleoside-diphosphate reductase activity

2|149

0.000213652

GO:0047485

protein N-terminus binding

6|149

0.000334432

GO:0016651

oxidoreductase activity, acting on NAD(P)H

6|149

0.000405851

GO:0009055

electron transfer activity

6|149

0.00042544

GO:0034061

DNA polymerase activity

4|149

0.000434811

GO:0045296

cadherin binding

10|149

0.000454903

GO:0015036

disulfide oxidoreductase activity

4|149

0.000476266

GO:0015038

glutathione disulfide oxidoreductase activity

2|149

0.000704247

GO:0015035

protein disulfide oxidoreductase activity

3|149

0.00120311

GO:0004128

cytochrome-b5 reductase activity, acting onNAD(P)H

2|149

0.001462482

GO:0001882

nucleoside binding

10|149

0.001685683

GO:0017022

myosin binding

4|149

0.002016304

GO:0097718

disordered domain specific binding

3|149

0.002265406