Fig. 3
From: Hesperidin identified from Citrus extracts potently inhibits HCV genotype 3a NS3 protease
Inhibitory effect of Citrus extracts on the activity of NS3-NS4A. Citrus extracts significantly inhibited the activity of NS3-NS4A as measured through the validated FRET assay. The maximum inhibitory effect was measured for the C. paradisi mesocarp extract (IC50 value of 5.79 ± 1.44 µg/mL; A, followed by the C. sinesis fruit extract B, the C. aurantinum fruit extract C, the C. reticulata fruit extract D, and the C. limon fruit extract E