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Table 4 Various biochemical parameters in normal Sprague Dawley rats after a single administration of different doses of I. verum extract

From: Anti-glycation properties of Illicium verum Hook. f. fruit in-vitro and in a diabetic rat model

Groups

Glucose levels (mg/dL)

Urea (mg/dL)

Creatinine (mg/dL)

Total Bilirubin (mg/dL)

Direct Bilirubin (mg/dL)

SGPT (U/L)

ALP (U/L)

GAMMA GT (U/L)

Control

106 ± 13.0

27.75 ± 0.95

0.87 ± 0.05

0.21 ± 0.02

0.187 ± 0.01

74 ± 6.1

830.2 ±23.21

5.5 ± 0.39

I. verum 500 mg/ kg

96 ± 6.21

29.2 ± 6.1

0.87 ± 0.09

0.18 ± 0.05

0.180 ± 0.04

76.7 ± 21.2

829 ± 6.68

5.5 ± 0.9

I. verum 1,000 mg/ kg

108.6 ± 15.8

34.0 ± 1.7

0.83 ± 0.11

0.2 ± 0.02

0.170 ± 0.02

62.3 ± 15.5

815 ± 18.5

5.6 ± 0.5

I. verum 1,500 mg/ kg

113.3 ± 10.01

35.3 ± 8.9

0.83 ± 0.1

0.2 ± 0.06

0.180 ± 0.03

68.3 ± 11.6

850.3 ± 11.13*

6.0 ± 1.0

I. verum 2,000 mg/ kg

118.3 ± 6.65

38.3 ± 3.0

0.8 ± 00

0.3 ± 0.02

0.181 ± 0.01

55.0 ± 2.8

858 ± 16.9*

6.5 ± 0.7

  1. Each value presents mean ± S.D. (n = 6)
  2. 500 mg/kg, 1,000 mg/kg, 1,500 mg/kg and 2,000 mg/kg refer to different doses of Illicium verum administered to normal rats
  3. * Statistical significance vs. normal control (p < 0.001)