Fig. 9

Protective effect of AE and NDGA activity against induced oxidative (A) and nitrosative (B) stress on HDL-PON-1. HDL was incubated in either the presence or absence of 5 mM AAPH or 10 µM SIN-1 with or without AE or NDGA.PON-1 activity was determined by the capacity of the enzyme to hydrolyze phenylacetate. Results are expressed as Mean ± SEM of three or more experiments performed in triplicate. **p < 0.01 significantly different with respect to basal conditions and #p < 0.05, ##p < 0.01: significantly different with respect to AAPH (A) or SIN-1 (B) (One way ANOVA followed by Dunnett’s test)