Fig. 3
Effect of AE and NDGA on the production of NO by glucose-treated macrophages. A Effect of glucose on NO. B Effect of AE on NO in glucose-treated cells. C Effect of NDGA on the production of NO by glucose-treated cells. Cells were incubated for 24 h in presence of different concentrations of glucose: 5.5 (basal), 11 mM and 55 mM with or without AE or NDGA. Results represent total nitrites x 106 cells (nM) and are expressed as Mean ± SEM of three or more experiments performed in triplicate. The percentage of decrease is also expressed over the bar when necessary.* p <0.05, *** p < 0.001: significantly different with respect to basal conditions and # p < 0.05, ## p < 0.01, ### p < 0.001: significantly different with respect to each concentration of glucose (One way ANOVA followed by Dunnett’s test)