MAT Outcomes a | True AA | Sham AA | Standard Care | Chi-square Test | Effect Size | Post-hoc Analysis c |
---|
True vs. Sham | True vs. SC | Sham vs. SC |
---|
n b | No. of CR (%) | n | No. of CR (%) | n | No. of CR (%) | Value | p | Cramer’s V | Value | p | Value | p | Value | p |
---|
CR of overall CINV | 37 | 11 (29.7%) | 38 | 11 (28.9%) | 38 | 5 (13.2%) | 3.64 | 0.16 | 0.18 | NA | NA | NA | NA | NA | NA |
CR of acute CINV | 38 | 20 (52.6%) | 38 | 17 (44.7%) | 38 | 9 (23.7%) | 7.07 | 0.03 | 0.25 | 0.47 | 0.49 | 6.75 | 0.01 | 3.74 | 0.05 |
CR of delayed CINV | 37 | 16 (43.2%) | 38 | 16 (42.1%) | 38 | 13 (34.2%) | 0.76 | 0.68 | 0.08 | NA | NA | NA | NA | NA | NA |
CR of overall nausea | 37 | 11 (29.7%) | 38 | 11 (28.9%) | 38 | 5 (13.2%) | 3.64 | 0.16 | 0.18 | NA | NA | NA | NA | NA | NA |
CR of overall vomiting | 37 | 24 (64.9%) | 38 | 24 (63.2%) | 38 | 17 (44.7%) | 3.85 | 0.15 | 0.19 | NA | NA | NA | NA | NA | NA |
- This table is derived and modified from the original PhD thesis of Professor Jing-Yu (Benjamin) Tan [Tan, J. (2017). Effects of auricular acupressure on chemotherapy-induced nausea and vomiting in breast cancer patients: a preliminary randomized controlled trial. Doctoral dissertation, The Hong Kong Polytechnic University, Hong Kong.] [28]
- CINV chemotherapy-induced nausea and vomiting, MAT MASCC Antiemesis Tool, AA auricular acupressure, SC standard care, CR complete response, NA not applicable
- aCR of overall CINV: no nausea and vomiting from day 1 to day 5 of the first chemotherapy cycle; CR of acute CINV: no nausea and vomiting during day 1 of the first chemotherapy cycle; CR of delayed CINV: no nausea and vomiting from day 2 to day 5 of the first chemotherapy cycle; CR of overall nausea: no nausea from day 1 to day 5 of the chemotherapy cycle; CR of overall vomiting: no vomiting from day 1 to day 5 of the chemotherapy cycle
- bone participant from the true AT group dropped out during the delayed CINV assessment. ITT analysis using the acute phase data as the delayed outcomes is not appropriate here because the delayed CINV symptom is different from the acute CINV symptom in nature. No ITT approach was utilized in this analysis; therefore, the available sample size for calculating the CR of the overall CINV, delayed CINV, overall nausea, and overall vomiting in the true AT group was 37
- cpartitioning Chi-square statistics were applied for the post-hoc analysis