The effect of barberry (Berberis integerrima) on lipid profile and systemic inflammation in subjects with cardiovascular risk factors: a randomized controlled trial

Table 4 Measures of lipid profile in participant at the baseline and after 8 weeks

Variable	Time	Barberry group (n = 42)	Control group (n = 42)	p-value^b	p-value^c
TC (mg/dL)	baseline	168.18 ± 35.74	180.92 ± 29.93	0.08	0.011
	after 8 weeks	160.23 ± 35.80	183.62 ± 31.52	0.002
	p-value^a	0.06	0.55
LDL-C (mg/dL)	baseline	97.27 ± 36.22	107.64 ± 24.37	0.12	0.015
	after 8 weeks	89.72 ± 32.63	108.27 ± 25.45	0.005
	p-value^a	0.06	0.86
sd-LDL (mg/dL)	baseline	33.07 ± 18.16	35.89 ± 18.70	0.48	0.019
	after 8 weeks	29.61 ± 15.82	39.87 ± 21.25	0.014
	p-value^a	0.24	0.25
HDL-C (mg/dL)	baseline	44.41 ± 8.87	47.23 ± 9.31	0.15	0.21
	after 8 weeks	44.60 ± 10.70	45.23 ± 9.28	0.77
	p-value^a	0.87	0.022
TC/HDL-C	baseline	3.88 ± 0.91	3.92 ± 0.75	0.80	0.039
	after 8 weeks	3.76 ± 1.18	4.17 ± 0.83	0.07
	p-value^a	0.44	0.023
Non-HDL-C (mg/dL)	baseline	123.76 ± 33.20	133.69 ± 26.81	0.13	0.004
	after 8 weeks	115.58 ± 34.12	138.38 ± 29.45	0.002
	p-value^a	0.036	0.28
TG (mg/dL)	baseline	131.23 ± 46.16	122.56 ± 43.58	0.37	< 0.001
	after 8 weeks	113.69 ± 32.86	150.56 ± 60.35	0.001
	p-value^a	0.002	< 0.001

All values are means ± SD. HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; sd-LDL-C, small-dense low-density lipoprotein cholesterol; TG, triglycerdes; TC, total cholesterol
^aValues were compared using paired t-test
^bValues were compared using an independent t-test
^cValues were analyzed using the ANCOVA test with baseline values as a covariate

ISSN: 2662-7671