Table 7 Clinical chemistry of female rats treated with GlucoMedix® at 28 days
Group/dose (mg/kg) | GLU (mg/dL) | T-Chol (mg/dL) | TG (mg/dL) | AST (U/L) | ALT (U/L) | BUN (mg/dL) | Crea (mg/dL) | TSH (mIU/L) | T3 (mIU/L) | T4 (ug/dL) |
|---|---|---|---|---|---|---|---|---|---|---|
250 | 90.6 + 3.36 | 94.0 + 1.58 | 68.0 + 2.35 | 30.8 + 1.30 | 33.2 + 0.84 | 39.4 + 1.67 | 0.74 + 0.15 | 2.90 + 0.33 | 2.68 + 0.08 | 1.00 + 0.19 |
1000 | 87.0 + 2.74 | 95.2 + 1.92 | 64.6 + 1.67 | 29.8 + 1.30 | 31.6 + 2.07 | 37.0 + 1.58 | 0.7 + 0.16 | 2.76 + 0.38 | 2.54 + 0.23 | 0.90 + 0.27 |
2000 | 85.8 + 3.19 | 89.2 + 1.64 | 64.0 + 1.58 | 25.0 + 2.55 | 31.2 + 1.30 | 32.6 + 2.19 | 0.72 + 0.18 | 2.96 + 0.44 | 2.28 + 0.24 | 0.84 + 0.18 |
Control | 85.0 + 4.18 | 90.2 + 4.82 | 62.8 + 1.92 | 25.6 + 2.70 | 34.6 + 3.36 | 33.6 + 2.61 | 0.7 + 0.14 | 2.80 + 0.30 | 2.32 + 0.28 | 0.90 + 0.12 |