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Table 6 Body weight change in the 4-day suppressive test of the ethanolic wood extract of M. fragrans

From: Evaluation of the antimalarial activity and toxicity of Mahanil-Tang-Thong formulation and its plant ingredients

Group

Dose (mg/kg)

Day 0 (g)

Day 4 (g)

Change (%)

Negative control group

–

36.56 ± 1.25

35.17 ± 1.23

−3.82 ± 0.73b, d, e

Artesunate

6

35.95 ± 2.02

38.25 ± 2.07

6.42 ± 1.61a, c, d, e

Extract

200

35.91 ± 2.54

33.96 ± 2.31

−5.39 ± 1.50b, d, e

400

35.23 ± 2.49

34.52 ± 2.81

−2.06 ± 1.69a, b, c

600

34.23 ± 1.40

33.93 ± 1.35

−0.89 ± 0.18a, b, c

  1. The data are presented as the mean ± SEM (n = 5 per group)
  2. aCompared to negative control
  3. bCompared to artesunate
  4. cCompared to 200 mg/kg extract
  5. dCompared to 400 mg/kg extract
  6. eCompared to 600 mg/kg extract, p < 0.05