Table 4 In vitro antimalarial activity and cytotoxicity of medicinal plants in the Mahanil-Tang-Thong formulation
Medicinal Plant | Extract | pLDH: IC50 (μg/ml) | MTT: CC50 (μg/ml) |
|---|---|---|---|
Calamus axillaris Becc. | Ethanolic | 22.32 ± 0.00 | 54.69 ± 2.96 |
Aqueous | 52.37 ± 0.05 | >80 | |
Dracaena loureiri Gagnep. | Ethanolic | 10.47 ± 0.00 | 55.67 ± 3.28 |
Aqueous | 104.00 ± 0.00 | >80 | |
Entada rheedii Spreng. | Ethanolic | 365.40 ± 0.02 | >80 |
Aqueous | 203.60 ± 0.02 | 42.64 ± 0.14 | |
Myristica fragrans Houtt. | Ethanolic | 8.87 ± 0.00 | >80 |
Aqueous | 46.36 ± 0.01 | >80 | |
Pogostemon cablin (Blanco) | Ethanolic | 24.49 ± 0.01 | >80 |
Aqueous | 549.30 ± 0.07 | >80 | |
Sapindus rarak DC. | Ethanolic | 75.76 ± 0.00 | 41.11 ± 1.13 |
Aqueous | 90.84 ± 0.02 | 43.52 ± 2.06 | |
Spondias pinnata (L.f.) Kurz | Ethanolic | 2.46 ± 0.69 | 48.03 ± 0.04 |
Aqueous | 49.94 ± 0.00 | >80 | |
Tectona grandis L.f. | Ethanolic | 3.21 ± 0.00 | 29.11 ± 1.10 |
Aqueous | 120.00 ± 0.03 | >80 | |
Tiliacora triandra (Colebr.) Diels | Ethanolic | 116.50 ± 0.01 | >80 |
Aqueous | 117.00 ± 0.02 | >80 | |
Mahanil-Tang-Thong formulation | Ethanolic | 37.63 ± 1.05 | 28.50 ± 2.39 |
Aqueous | 100.49 ± 1.05 | 250.95 ± 5.25 | |
Artesunate | – | 1.28 ± 0.71 | ND |
Doxorubicin | – | ND | 1.23 ± 0.16 |