Table 1 Percentage of PC12 cells in each state after treatment with 6-OHDA, 6-OHDA + thymol 100 µM, 6-OHDA + thymol 150 µM. The data presented are mean ± SEM of two independent experiments
Compound/Concentration | Vital cells (%) An-/PI- | Early Apoptosis (%) An + /PI- | Late apoptosis (%) An + /PI + | Necrosis (%) An-/PI + |
|---|---|---|---|---|
Control | 96.05 ± 0.75 | 0.23 ± 0.05 | 1.90 ± 0.67 | 1.64 ± 0.64 |
6-OHDA 75 μM | 68.80 ± 3.00≈ | 2.10 ± 0.12 | 8.4 ± 1.1∼ | 27.80 ± 0.30≈ |
6-OHDA/Thymol 100 μM | 79.90 ± 1.8 | 2.31 ± 0.79 | 5.92 ± 0.88 | 17.76 ± 2.36 |
6-OHDA/Thymol 150 μM | 87.00 ± 2.7* | 3.01 ± 0.98 | 6.59 ± 0.61 | 15.76 ± 2.96* |