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Table 1 Percentage of PC12 cells in each state after treatment with 6-OHDA, 6-OHDA + thymol 100 µM, 6-OHDA + thymol 150 µM. The data presented are mean ± SEM of two independent experiments

From: Thymol protects against 6-hydroxydopamine-induced neurotoxicity in in vivo and in vitro model of Parkinson’s disease via inhibiting oxidative stress

Compound/Concentration Vital cells (%) An-/PI- Early Apoptosis (%) An + /PI- Late apoptosis (%) An + /PI +  Necrosis
(%) An-/PI + 
Control 96.05 ± 0.75 0.23 ± 0.05 1.90 ± 0.67 1.64 ± 0.64
6-OHDA 75 μM 68.80 ± 3.00 2.10 ± 0.12 8.4 ± 1.1 27.80 ± 0.30
6-OHDA/Thymol 100 μM 79.90 ± 1.8 2.31 ± 0.79 5.92 ± 0.88 17.76 ± 2.36
6-OHDA/Thymol 150 μM 87.00 ± 2.7* 3.01 ± 0.98 6.59 ± 0.61 15.76 ± 2.96*
  1. p < 0.05 and ≈ p < 0.01 compared with control, *p < 0.05 compared with 6-OHDA