|  | Dose of black ginseng extract (mg/kg) | |||
---|---|---|---|---|---|
0 | 500 | 1000 | 2000 | ||
Male (n = 10/group) | |||||
 Liver | (g) | 13.94 ± 0.85 | 13.03 ± 3.58 | 13.48 ± 2.53 | 14.06 ± 1.65 |
(g%) | 3.47 ± 0.22 | 3.21 ± 0.91 | 3.45 ± 0.57 | 3.54 ± 0.41 | |
 Spleen | (g) | 0.94 ± 0.64 | 0.81 ± 0.11 | 0.72 ± 0.13 | 0.82 ± 0.12 |
(g%) | 0.23 ± 0.16 | 0.20 ± 0.03 | 0.19 ± 0.03 | 0.21 ± 0.03 | |
 Kidney (R) | (g) | 1.46 ± 0.13 | 1.51 ± 0.19 | 1.41 ± 0.16 | 1.47 ± 0.11 |
(g%) | 0.36 ± 0.03 | 0.37 ± 0.04 | 0.36 ± 0.03 | 0.37 ± 0.02 | |
 Kidney (L) | (g) | 1.42 ± 0.10 | 1.46 ± 0.17 | 1.43 ± 0.13 | 1.42 ± 0.12 |
(g%) | 0.35 ± 0.02 | 0.36 ± 0.03 | 0.37 ± 0.02 | 0.36 ± 0.03 | |
 Adrenal gl. (R) | (g) | 0.024 ± 0.002 | 0.028 ± 0.006 | 0.026 ± 0.005 | 0.026 ± 0.004 |
(g%) | 0.006 ± 0.001 | 0.007 ± 0.001 | 0.007 ± 0.001 | 0.007 ± 0.001 | |
 Adrenal gl. (L) | (g) | 0.026 ± 0.005 | 0.027 ± 0.005 | 0.025 ± 0.004 | 0.028 ± 0.003 |
(g%) | 0.007 ± 0.001 | 0.007 ± 0.001 | 0.006 ± 0.001 | 0.007 ± 0.001 | |
 Testis (R) | (g) | 1.58 ± 0.13 | 1.58 ± 0.11 | 1.52 ± 0.12 | 1.56 ± 0.16 |
(g%) | 0.39 ± 0.04 | 0.39 ± 0.03 | 0.39 ± 0.04 | 0.39 ± 0.05 | |
 Testis (L) | (g) | 1.59 ± 0.13 | 1.59 ± 0.12 | 1.49 ± 0.11 | 1.55 ± 0.17 |
(g%) | 0.40 ± 0.04 | 0.39 ± 0.03 | 0.38 ± 0.04 | 0.39 ± 0.05 | |
 Thymus | (g) | 0.47 ± 0.10 | 0.66 ± 0.51 | 0.50 ± 0.12 | 0.43 ± 0.12 |
(g%) | 0.12 ± 0.02 | 0.16 ± 0.11 | 0.13 ± 0.03 | 0.11 ± 0.03 | |
 Heart | (g) | 1.31 ± 0.09 | 1.22 ± 0.25 | 1.27 ± 0.05 | 1.28 ± 0.05 |
(g%) | 0.33 ± 0.02 | 0.30 ± 0.07 | 0.33 ± 0.02 | 0.32 ± 0.02 | |
 Lung | (g) | 1.39 ± 0.11 | 1.43 ± 0.11 | 1.38 ± 0.12 | 1.47 ± 0.15 |
(g%) | 0.35 ± 0.02 | 0.35 ± 0.04 | 0.35 ± 0.03 | 0.37 ± 0.03 | |
 Brain | (g) | 2.04 ± 0.05 | 1.96 ± 0.19 | 2.04 ± 0.10 | 2.06 ± 0.09 |
(g%) | 0.51 ± 0.02 | 0.48 ± 0.06 | 0.53 ± 0.05 | 0.52 ± 0.03 | |
 Pituitary gl. | (g) | 0.015 ± 0.005 | 0.016 ± 0.008 | 0.012 ± 0.002 | 0.013 ± 0.004 |
(g%) | 0.0037 ±0.0013 | 0.0038 ±0.0019 | 0.0032 ± 0.0005 | 0.0032 ±0.0009 | |
Female (n = 10/group) | |||||
 Liver | (g) | 7.95 ± 1.06 | 8.22 ± 0.87 | 7.90 ± 0.77 | 8.38 ± 0.71* |
(g%) | 3.35 ± 0.23 | 3.37 ± 0.26 | 3.28 ± 0.18 | 3.44 ± 0.13 | |
 Spleen | (g) | 0.51 ± 0.05 | 0.59 ± 0.14 | 0.50 ± 0.07 | 0.69 ± 0.26 |
(g%) | 0.22 ± 0.03 | 0.24 ± 0.04 | 0.21 ± 0.03 | 0.28 ± 0.09* | |
 Kidney (R) | (g) | 0.84 ± 0.08 | 0.85 ± 0.19 | 0.88 ± 0.11 | 0.88 ± 0.08 |
(g%) | 0.36 ± 0.03 | 0.35 ± 0.07 | 0.36 ± 0.02 | 0.36 ± 0.02 | |
 Kidney (L) | (g) | 0.82 ± 0.07 | 0.88 ± 0.10 | 0.86 ± 0.10 | 0.86 ± 0.08 |
(g%) | 0.35 ± 0.03 | 0.36 ± 0.03 | 0.36 ± 0.02 | 0.36 ± 0.02 | |
 Adrenal gl. (R) | (g) | 0.033 ± 0.004 | 0.033 ± 0.003 | 0.033 ± 0.005 | 0.036 ± 0.004 |
(g%) | 0.014 ± 0.002 | 0.014 ± 0.001 | 0.014 ± 0.003 | 0.015 ± 0.002 | |
 Adrenal gl. (L) | (g) | 0.035 ± 0.005 | 0.034 ± 0.004 | 0.033 ± 0.005 | 0.036 ± 0.004 |
(g%) | 0.015 ± 0.002 | 0.014 ± 0.001 | 0.014 ± 0.002 | 0.015 ± 0.002 | |
 Ovary (R) | (g) | 0.043 ± 0.007 | 0.043 ± 0.008 | 0.043 ± 0.010 | 0.047 ± 0.005 |
(g%) | 0.018 ± 0.003 | 0.018 ± 0.003 | 0.018 ± 0.004 | 0.019 ± 0.003 | |
 Ovary (L) | (g) | 0.044 ± 0.010 | 0.043 ± 0.006 | 0.041 ± 0.006 | 0.044 ± 0.004 |
(g%) | 0.018 ± 0.004 | 0.018 ± 0.003 | 0.017 ± 0.003 | 0.018 ± 0.002 | |
 Thymus | (g) | 0.41 ± 0.07 | 0.46 ± 0.07 | 0.49 ± 0.14 | 0.52 ± 0.12 |
(g%) | 0.17 ± 0.02 | 0.19 ± 0.03 | 0.20 ± 0.04 | 0.21 ± 0.04 | |
 Heart | (g) | 0.87 ± 0.09 | 0.88 ± 0.07 | 0.85 ± 0.06 | 0.87 ± 0.10 |
(g%) | 0.37 ± 0.02 | 0.36 ± 0.03 | 0.35 ± 0.02 | 0.36 ± 0.02 | |
 Lung | (g) | 1.05 ± 0.07 | 1.10 ± 0.08 | 1.04 ± 0.09 | 1.10 ± 0.08 |
(g%) | 0.45 ± 0.04 | 0.45 ± 0.03 | 0.44 ± 0.04 | 0.45 ± 0.03 | |
 Brain | (g) | 1.90 ± 0.09 | 1.87 ± 0.09 | 1.85 ± 0.08 | 1.92 ± 0.09 |
(g%) | 0.81 ± 0.06 | 0.77 ± 0.05 | 0.77 ± 0.06 | 0.79 ± 0.04 | |
 Pituitary gl. | (g) | 0.015 ± 0.001 | 0.017 ± 0.002 | 0.016 ± 0.005 | 0.020 ± 0.004* |
(g%) | 0.0062 ± 0.0007 | 0.0068 ± 0.0009 | 0.0068 ± 0.0021 | 0.0082 ± 0.0021* |