Table 1 IC50 for cytotoxic activity of black ginseng extract in human cancer cell lines
Test substance | IC50 | |||||
|---|---|---|---|---|---|---|
A-431 | A549 | HT-29 | NCI-N87 | Capan-1 | HepG2 | |
BGE (μg/mL) | 1302.1 ± 7.1 | 1461.4 ± 22.2** | 1228.0 ± 19.9 | 1528.6 ± 55.2** | 1453.4 ± 20.0** | 1357.7 ± 30.3 |
RGE (μg/mL) | >  5000.0 | >  5000.0 | >  5000.0 | >  5000.0 | >  5000.0 | >  5000.0 |
20(S)-Rg3 (μg/mL) | 268.7 ± 7.4 | 262.9 ± 5.5 | 300.0 ± 5.0* | 251.7 ± 1.0 | 269.2 ± 5.3 | 212.0 ± 20.3** |
Rg5 (μg/mL) | 39.2 ± 2.9 | 42.8 ± 8.5 | 50.0 ± 5.2 | 29.4 ± 0.6 | 41.6 ± 3.1 | 57.9 ± 2.6** |
Paclitaxel (nM) | 3.6 ± 0.3 | 4.0 ± 1.9 | 0.9 ± 0.3 | 118.8 ± 53.6** | 21.5 ± 5.7 | 1.0 ± 0.1 |