In vitro and in vivo evaluations of antioxidative, anti-Alzheimer, antidiabetic and anticancer potentials of hydroponically and soil grown Lactuca sativa

Naseem, Shahid; Ismail, Hammad

doi:10.1186/s12906-022-03520-5

BMC Complementary Medicine and Therapies

Table 2 Effect of hydroponically (HyL) and soil-grown (SoL) lettuce on blood glucose level (mg/dL)

From: In vitro and in vivo evaluations of antioxidative, anti-Alzheimer, antidiabetic and anticancer potentials of hydroponically and soil grown Lactuca sativa

Groups	0 h	3^rdhour	6^thhour	12^thhour	2^ndday	6^thday	10^thday	14^thday	18^thday	21^stday
Normal control	99 ± 2.6^abcde	97 ± 3.1^abcde	98 ± 2.4^abcde	95 ± 4.0^abcde	93 ± 3.4^abcde	95 ± 3.0^abcde	92 ± 2.2^abcde	98 ± 3.6^abcde	99 ± 1.3^abcde	97 ± 4.2^abcde
Diabetic control	405 ± 4.1^bcdf	528 ± 2.3^abcdf	510 ± 4.2^abcdf	515 ± 3.9^abcdf	505 ± 3.4^abcdf	501 ± 2.5^abcdf	490 ± 3.6^abcdf	495 ± 4.5^abcdf	492 ± 2.1^abcdf	489 ± 3.2^abcdf
Glibenclamide 10mg/kg	410 ± 1.9^bcdf	131 ± 1.2^bcdef	105 ± 4.3^bcdef	103 ± 2.8^bcdef	101 ± 3.4^bcdef	105 ± 3.1^bcdef	95 ± 2.5^bcdef	97 ± 2.2^bcdef	96 ± 2.8^bcdef	97 ± 1.1^bcdef
HyL 200mg/kg	415 ± 4.2^bcdef	250 ± 3.2^abcdef	187 ± 2.9^abcdef	162 ± 1.9^abcdef	145 ± 3.0^abcdef	138 ± 1.8^abcdef	135 ± 1.4^abcdef	132 ± 3.1^abcdef	131 ± 4.2^abcdef	126 ± 4.4^abcdef
HyL 100mg/kg	412 ± 5.1^bcdef	247 ± 4.2^abdef	225 ± 3.5^adef	198 ± 3.6^abcdef	195 ± 4.8^acdef	190 ± 5.6^abcdef	185 ± 6.3^abcdef	183 ± 5.2^abcdef	183 ± 4.8^abcdef	180 ± 3.5^abcdef
HyL 50mg/kg	405 ± 3.6^bcdef	255 ± 5.1^abcdef	235 ± 5.7^abcdef	210 ± 4.9^adef	205 ± 4.7^abdef	206 ± 4.3^abdef	209 ± 4.8^abcdef	208 ± 5.9^abdef	203 ± 6.2^abdef	206 ± 4.2^abdef
SoL 200mg/kg	395 ± 3.2^acdef	310 ± 3.4^abdef	228 ± 2.5^acdef	206 ± 2.8^adef	196 ± 3.4^acdef	184 ± 3.6^acdef	176 ± 1.9^acdef	175 ± 1.3^acdef	172 ± 3.5^acdef	165 ± 2.4^acdef
SoL 100mg/kg	310 ± 4.1^abdef	242 ± 5.0^abdef	220 ± 4.6^abdef	210 ± 2.9^adef	205 ± 6.1^abdef	203 ± 4.7^abdef	202 ± 5.1^abdef	210 ± 4.5^abdef	200 ± 4.1^abdef	201 ± 5.7^abdef
SoL 50mg/kg	350 ± 5.2^abcef	260 ± 5.6^abcef	242 ± 6.1^abcef	235 ± 3.5^abcef	228 ± 4.8^abcef	224 ± 5.2^abcef	232 ± 5.9^abcef	226 ± 6.1^abcef	231 ± 5.3^abcef	231 ± 6.2^abcef

Values expressed as means (n = 7) ± SD with *p < 0.05 in comparison with Glibenclamide representing “a”, SoL 200 mg/kg representing “b”, SoL 100 mg/kg representing “c”, SoL 50 mg/kg representing “d”, diabetic control representing “e” and normal control representing “f” with all respective concentrations of HyL and controls

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ISSN: 2662-7671

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