Skip to main content

Table 2 Effect of Euphorbia helioscopia on Amylin, Leptin and Thyroid hormones

From: Attenuation of carbohydrate metabolism and lipid profile by methanolic extract of Euphorbia helioscopia and improvement of beta cell function in a type 2 diabetic rat model

Groups Amylin (pg/ml)
p = 0.007
Leptin (ng/ml)
p = 0.039
T3 (pg/ml)
p = 0.019
T4 (ng/ml)
p = 0.018
TSH (ng/ml)
P = 0.03
NC 1736.35 ± 75.97a 1.06 ± 0.32ab 48.44 ± 0.47ab 59.97 ± 13.13ab 84.90 ± 21.38ab
PC 2962.45 ± 213.81c 1.81 ± .39b 40.66 ± 6.42a 18.94 ± 3.08a 51.42 ± 28.63a
SC 2075.1 ± 40.67ab 1.425 ± 0.19ab 54.97 ± 10.19ab 74.55 ± 14.94b 125.24 ± 11.71b
EH1 2078.19 ± 55.38ab 1.12 ± 0.05ab 70.35 ± 5.52ab 67.27 ± 9.38ab 117.03 ± 4.17ab
EH2 2317.53 ± 63.15b 0.67 ± 0.06a 77.35 ± 4.59b 73.67 ± 14.11b 123.09 ± 8.97ab
  1. Data are expressed as means ± standard errors of a total of 8 samples for each group. Values having different lowercase letters in a column are significantly different (P ≤ 0.05). NC, negative control group; PC, positive control group (Diabetic rats without any treatment); SC (Standard control group (Diabetic rats treated with metformin at 1 mg/kg body weight via oral lavage); EH1, Treatment group-I (Diabetic rats given methanolic extract of Euphorbia helioscopia at dose of 200 mg/Kg BW via oral lavage); EH2, Treatment group-II (Diabetic rats given methanolic extract of Euphorbia helioscopia at dose of 400 mg/Kg BW via oral lavage; T3, triiodothyronine; T4, thyroxin, TSH; thyroid stimulating hormone