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Table 1 Effect of Euphorbia helioscopia on oxidative stress markers

From: Attenuation of carbohydrate metabolism and lipid profile by methanolic extract of Euphorbia helioscopia and improvement of beta cell function in a type 2 diabetic rat model

Groups PON1 (U/L)
p = 0.005
ARY (KU/L)
p = 0.006
TAC (mM/L)
p = 0.036
TOS (uM/L)
p = 0.001
MDA (pM/dl)
p = 0.02
Catalase (KU/min)
p = 0.0
SOD (ng/ml)
p = 0.041
NC 18.60 ± 3.62a 140.88 ± 5.5ab 1.17 ± 0.2ab 22.56 ± 4.72ab 1.66 ± 0.34ab 16.93 ± 2.06ab 7.83 ± 0.16ab
PC 17.18 ± 0.98a 125.71 ± 1.78a 1.04 ± 0.41a 31.13 ± 3.34b 2.64 ± 0.47bc 10.07 ± 0.71a 5.17 ± 0.8a
SC 24.59 ± 0.53ab 147.18 ± 6.83ab 1.4 ± 0.17ab 23.26 ± 1.97ab 1.06 ± 0.21ab 17.56 ± 0.68b 6.52 ± 0.89ab
EH1 26.24 ± 2.57ab 145.29 ± 6.31ab 1.61 ± 0.2ab 18.94 ± 0.82a 1.17 ± 0.28bc 19.37 ± 4.29b 7.87 ± 0.15ab
EH 2 31.28 ± 3.58b 163.41 ± 7.77b 2.5 ± 0.47b 12.97 ± 0.61a 0.82 ± 0.5a 31.18 ± 1.78c 8.39 ± 1.06b
  1. Data are expressed as means ± standard errors of a total of 8 samples for each group. Values with different letters in a column are significantly different (P ≤ 0.05). NC, negative control group; PC, positive control group (Diabetic rats without any treatment); SC (Standard control group (Diabetic rats treated with metformin at 1 mg/kg body weight via oral lavage); EH1, Treatment group-I (Diabetic rats given methanolic extract of Euphorbia helioscopia at dose of 200 mg/Kg BW via oral lavage); EH2, Treatment group-II (Diabetic rats given methanolic extract of Euphorbia helioscopia at dose of 400 mg/Kg BW via oral lavage); PON1, Paraoxonase activity; ARY, Arylesterase activity, TAC; Total antioxidant capacity, TOS; Total oxidant status, SOD; Superoxide dismutase