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Table 4 The results of CELLO

From: Screening the components of Saussurea involucrata for novel targets for the treatment of NSCLC using network pharmacology

Compounds

Protein

PDB ID

Location

RELIABILITY

Approach

UniProt ID

Luteolin

Quercetin

Kaempferol

MMP1

966C

Extracellular

Cytoplasmic

2.122*

2.074*

SVM-RFE

P03956

Quercetin

MMP3

1HY7

Cytoplasmic

3.373*

SVM-RFE

P08254

Quercetin

NQO1

5FUQ

InnerMembrane

Cytoplasmic

Periplasmic

1.851*

1.311*

1.209*

SVM-RFE

P15559

Quercetin

Luteolin

EGFR

3W2S

Cytoplasmic

Nuclear

2.510*

1.183

SVM-RFE

P00533

Luteolin

MET

4EEV

Cytoplasmic

InnerMembrane

3.156*

1.166

SVM-RFE

P08581

Quercetin

MPO

5WDJ

Nuclear

1.215*

SVM-RFE

P05164