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Table 3 The results of PSORT II

From: Screening the components of Saussurea involucrata for novel targets for the treatment of NSCLC using network pharmacology

Compounds

Protein

PDB ID

Location (k=23)

Certainty (%)

Approach

UniProt ID

Luteolin

Quercetin

Kaempferol

MMP1

966C

cytoplasmic

mitochondrial

nuclear

39.1%

26.1%

21.7%

k-NN

P03956

Quercetin

MMP3

1HY7

mitochondrial

cytoplasmic

56.5%

30.4%

k-NN

P08254

Quercetin

NQO1

5FUQ

mitochondrial

cytoplasmic

nuclear

47.8%

21.7%

17.4%

k-NN

P15559

Quercetin

Luteolin

EGFR

3W2S

cytoplasmic

nuclear

69.6%

21.7%

k-NN

P00533

Luteolin

MET

4EEV

cytoplasmic

nuclear

mitochondrial

43.5%

30.4%

26.1%

k-NN

P08581

Quercetin

MPO

5WDJ

nuclear

cytoplasmic

78.3%

13.0%

k-NN

P05164