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Fig. 6 | BMC Complementary Medicine and Therapies

Fig. 6

From: Panax notoginseng saponins reverse P-gp-mediated steroid resistance in lupus: involvement in the suppression of the SIRT1/FoxO1/MDR1 signalling pathway in lymphocytes

Fig. 6

Th17 might be the main effector cell of PNS reversing SR in lupus. The expression of P-gp in different T-cells phenotypes from SLCs and SLCs/MP were detected by flow cytometry. (A) The expression of P-gp in CD8 + T cells. (B)The expression of P-gp in Th1 cells. (C) The expression of P-gp in Th2 cells. (D) The expression of P-gp in Th17 cells. (E) The expression of P-gp in Treg cells. (E) The expression of P-gp in Th17 cells treated by PNS. Experiments were repeated three times and data are expressed as the means ± SD. #P < 0.05 vs. SLCs. *P < 0.05 vs. SLCs/MP

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