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Table 2 Effects of crude extract and solvent fractions of the leaf of B.abyssinica on enteropooling

From: Evaluation of the antidiarrheal activity of 80% methanol extract and solvent fractions of the leaf of Bersama abyssinica fresen (Melianthaceae) in mice

Types of treatment Weight of intestinal contents (g) The volume of the intestinal contents (ml) Reduction of weight of intestinal contents (%) Reduction of volume of the intestinal contents (%)
NC 0.85 ± 0.04 0.72 ± 0.05 ––––––– –––––––
Loperamide 3 mg/kg 0.26 ± 0.04 0.18 ± 0.04 69.41 75.00
Crude extract (mg/kg)
 100 0.61 ± 0.03a2b3e3 0.50 ± 0.05a2b3e3 28.24 30.56
 200 0.48 ± 0.04a3b2 0.37 ± 0.04a3b1 43.53 48.61
 400 0.33 ± 0.03a3c3 0.21 ± 0.03a3c3 61.18 70.83
AF(mg/kg)
 100 0.64 ± 0.02 a2b3e3 0.54 ± 0.02a2b3e2 24.71 25.00
 200 0.50 ± 0.03a3b3 0.46 ± 0.03a3b3 41.18 36.11
 400 0.35 ± 0.03a3c3 0.31 ± 0.03a3c2 58.82 56.94
CF(mg/kg)
 100 0.67 ± 0.02 a1b3 0.57 ± 0.02 b3 21.18 20.83
 200 0.66 ± 0.04a2b3 0.55 ± 0.04a2b3 22.35 23.61
 400 0.53 ± 0.04a3 b3 0.42 ± 0.04a3b2 37.65 41.67
NHF(mg/kg)
 100 0.81 ± 0.04 b3 0.69 ± 0.05 b3 4.71 4.17
 200 0.79 ± 0.03 b3 0.68 ± 0.03 b3 7.06 5.56
 400 0.67 ± 0.04 a1b3 0.53 ± 0.04a1 b3 21.18 20.83
  1. Results are expressed as mean ± SEM (n = 6); statistical analysis was performed using one-way ANOVA followed by Tukey’s post hoc test. acompared to negative control, bcompared to loperamide, ccompared to 100 mg/kg, dcompared to 200 mg/kg, ecompared to 400 mg/kg. 1p < 0.05, 2p < 0.01, 3p < 0.001. NC negative control