Fig. 5
Mechanism of acacetin in peritoneal metastasis of GC in nude mice. A Tumours were implanted in the abdomen, and then, the gross and microscopic pathological features of metastatic nodules in the livers of mice were observed. B The number of cancerous nodules colonizing the abdomen. C Changes in body weight in nude mice. D Difference in EMT-related protein expression in liver metastatic nodules of mice treated with different concentrations of acacetin. Data are expressed as the mean ± SD (n = 3). * p < 0.05, ** p < 0.01, *** p < 0.001 compared to the control group