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Table 3 Analysis of Variance of the Regression Model

From: Optimization for ultrasonic-microwave synergetic extraction of total iridoid glycosides and screening of analgesic and anti-inflammatory active fractions from patrinia scabra Bunge (Valerianaceae)

Variance source

Sum of squares

Degree of freedom

Mean square

F value

P value

Model

549.8

14

39.27

665.73

<  0.0001**

A

12.86

1

12.86

217.93

<  0.0001**

B

68.44

1

68.44

1160.19

<  0.0001**

C

0.4342

1

0.4342

7.36

0.0168*

D

0.4503

1

0.4503

7.63

0.0153*

AB

0.0291

1

0.0291

0.493

0.4941

AC

0.2264

1

0.2264

3.84

0.0703

AD

0.6442

1

0.6442

10.92

0.0052**

BC

0.0133

1

0.0133

0.226

0.6418

BD

0.0021

1

0.0021

0.0358

0.8526

CD

0.0001

1

0.0001

0.0009

0.9763

A2

77.45

1

77.45

1312.91

<  0.0001**

B2

419.07

1

419.07

7104.14

<  0.0001**

C2

5.52

1

5.52

93.61

<  0.0001**

D2

0.1649

1

0.1649

2.8

0.1167

Residual

0.8259

14

0.059

  

Lack of Fit

0.5438

10

0.0544

0.7710

0.6649

Pure error

0.2821

4

0.0705

  

Total deviation

550.62

28

   

R2 = 0.9985 Radj2 = 0.9970

  1. Note: A ethanol concentration (%), B material-to-liquid ratio (g.mL−1), C microwave power (W), D extraction time (min), ** represents extremely significant (P < 0.01), * represents significant (P < 0.05)