| Curcumin | Trans-resveratrol | Quercetin | (1 s,4 s)-Eucalyptol |
---|---|---|---|---|
(1) ProTox-II | ||||
 Predicted LD50 (mg/kg) | 2000 | 1560 | 159 | 2480 |
 Predicted toxicity class | 4 | 4 | 3 | 5 |
 Average similarity (%) | 100 | 69.97 | 100 | 100 |
 Prediction accuracy (%) | 100 | 68.07 | 100 | 100 |
(2) Pred-hERG | ||||
 Prediction/Potency | Non-cardiotoxic | Non-cardiotoxic | Non-cardiotoxic | Potential cardiotoxic (Weak or moderate) |
 Confidence (%) | 70 | 60 | 60 | 80 |
 Applicability domain (AD) | Yes (Value = 0.28 and limit = 0.26) | No (Value = 0.21 and limit = 0.26) | No (Value = 0.19 and limit = 0.26) | No (Value = 0.16 and limit = 0.26) |