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Fig. 4 | BMC Complementary Medicine and Therapies

Fig. 4

From: The antioxidant and anti-inflammatory effects of Carica Papaya Linn. seeds extract on CCl4-induced liver injury in male rats

Fig. 4

Representative microscopic images of H & E stained liver sections of all studied groups. C group: liver demonstrating the normal organization of hepatocytes and hepatic lobules. SE group: Hepatocytes showing of rat liver with cytoplasmic vacuolation in most cells. CCl4 group: revealing focal areas with eosinophilic hepatocytes (*) alternating with areas of pale vacuolated hepatocytes (•). Some portal tracts PT show dense cellular infiltration and fibers in between. There are groups of degenerated hepatocytes with loss of nuclei. SE group: liver section showing preserved normal liver architecture (arrow). SE-CCl4: regaining the eosinophilic granular appearance of the cytoplasm in hepatocytes. The central vein and portal vein tributary in the portal tract area abnormally approximated denoting persistently disrupted the architecture of the liver lobule (arrow). They show dilatation and engorgement with blood cells in the lumen (*). SE-CCl4-SE group: showing apparent recovery of the architecture of hepatic lobule. Normal hepatocytes arranged in cords radiating from the central vein with clear sinusoids of average size

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