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Fig. 6 | BMC Complementary Medicine and Therapies

Fig. 6

From: Astragalus mongholicus Bunge and Panax notoginseng formula (A&P) improves renal mesangial cell damage in diabetic nephropathy by inhibiting the inflammatory response of infiltrated macrophages

Fig. 6

Mincle is the key to A&P to improve mesangial cell damage by down-regulating macrophage inflammation. a, The mRNA expression of Mincle in BMDM cells detected by Real-time PCR analysis. b-d, The protein level of Mincle in BMDM cells detected by western boltting analysis. e-g, The mRNA expression of TNF-α, IL-1β and IL-6 in co-culture cells detected by Real-time PCR analysis. h-l, The protein level of p-NFκB, TNF-α, IL-1β and IL-6 in co-culture cells detected by western boltting analysis. (The data are expressed as the mean ± SD. Compared with Control group, *P < 0.01. Compared with HG group, #P < 0.05, **P < 0.05. Compared with HG + A&P group, ##P < 0.05)

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