Hematological parameters | Control group | A. vera whole leaf extract dose levels in mg/kg | A. vera green rind extract dose levels in mg/kg | ||||
---|---|---|---|---|---|---|---|
200 | 400 | 800 | 200 | 400 | 800 | ||
Combined male and female | |||||||
 WBC (× 109/L) | 11.8 ± 1.24 | 11.6 ± 1.18 | 13.1 ± 2.60 | 13.1 ± 0.57 | 9.9 ± 1.06 | 9.9 ± 1.53 | 12.0 ± 1.6 |
 NEU (× 109/L) | 2.3 ± 0.40 | 3.0 ± 0.54 | 3.2 ± 0.79 | 2.3 ± 0.19 | 2.3 ± 0.29 | 2.4 ± 0.46 | 2.9 ± 0.33 |
 LYM(× 109/L) | 8.3 ± 1.14 | 7.2 ± 0.89 | 8.4 ± 1.89 | 9.4 ± 0.50 | 6.4 ± 1.02 | 6.4 ± 0.92 | 7.7 ± 1.45 |
 MONO (× 109/L) | 0.8 ± 0.17 | 0.7 ± 0.09 | 1.0 ± 0.21 | 0.8 ± 0.11 | 0.7 ± 0.08 | 0.6 ± 0.17 | 0.8 ± 0.14 |
 EOS (× 109/L) | 0.27 ± 0.06 | 0.64 ± 0.09** | 0.43 ± 0.09 | 0.49 ± 0.08 | 0.4 ± 0.06 | 0.4 ± 0.15 | 0.5 ± 0.06 |
 BASO (× 109/L) | 0.002 ± 0.002 | 0.0 ± 0.00 | 0.0 ± 0.00 | 0.0 ± 0.00 | 0.0 ± 0.00 | 0.0 ± 0.00 | 0.0 ± 0.00 |
 RBC (× 1012/L) | 7.7 ± 0.50 | 8.4 ± 0.35 | 8.6 ± 0.16 | 8.8 ± 0.37 | 8.6 ± 0.23 | 8.7 ± 0.37 | 8.7 ± 0.23 |
 Hb (g/dL) | 13.7 ± 0.81 | 14.5 ± 0.68 | 15.0 ± 0.21 | 15.4 ± 0.37 | 15.3 ± 0.38 | 15.2 ± 0.56 | 15.6 ± 0.34 |
 HCT (%) | 41.0 ± 2.71 | 46.0 ± 2.25 | 46.2 ± 0.81 | 47.62 ± 1.03 | 48.97 ± 0.80** | 48.70 ± 1.56** | 48.33 ± 1.30** |
 MCV (fL) | 53.12 ± 1.23 | 54.73 ± 1.15 | 53.73 ± 1.03 | 54.12 ± 1.43 | 56.87 ± 0.72 | 56.10 ± 1.62 | 55.12 ± 0.40 |
 MCH (pg) | 17.82 ± 0.26 | 17.38 ± 0.23 | 17.55 ± 0.18 | 17.53 ± 0.33 | 17.78 ± 0.09 | 17.50 ± 0.35 | 17.88 ± 0.11 |
 MCHC (g/dL) | 33.58 ± 0.42 | 31.73 ± 0.33** | 32.68 ± 0.30 | 32.45 ± 0.37 | 31.30 ± 0.37** | 31.30 ± 0.40** | 32.47 ± 0.21 |
 RDW-CV (%) | 19.22 ± 1.33 | 19.68 ± 0.58 | 20.22 ± 0.35 | 20.35 ± 0.72 | 19.28 ± 0.25 | 19.48 ± 0.83 | 19.93 ± 0.87 |
 PLT(× 109/L) | 886.80 ± 143.80 | 732.0 ± 24.7 | 766.0 ± 49.0 | 742.7 ± 24.7 | 743.7 ± 46.53 | 774.0 ± 26.41 | 807.3 ± 68.63 |
Females | |||||||
 WBC (× 109/L) | 10.72 ± 3.11 | 12.56 ± 1.02 | 14.28 ± 5.23 | 12.63 ± 1.05 | 10.98 ± 1.87 | 8.42 ± 1.23 | 10.48 ± 0.77 |
 NEU (× 109/L) | 1.74 ± 0.14 | 2.32 ± 0.13 | 2.90 ± 0.77 | 2.36 ± 0.29 | 2.19 ± 0.16 | 1.87 ± 0.45 | 2.36 ± 0.13 |
 LYM (× 109/L) | 9.32 ± 1.77 | 8.73 ± 0.72 | 9.63 ± 4.00 | 9.11 ± 1.05 | 7.58 ± 1.74 | 5.79 ± 0.66 | 6.77 ± 0.70 |
 MONO (× 109/L) | 0.83 ± 0.12 | 0.78 ± 0.06 | 1.27 ± 0.37 | 0.78 ± 0.23 | 0.77 ± 0.09 | 0.45 ± 0.11 | 0.90 ± 0.14 |
 EOS (× 109/L) | 0.19 ± 0.06 | 0.73 ± 0.18 | 0.32 ± 0.06 | 0.37 ± 0.05 | 0.45 ± 0.09 | 0.31 ± 0.08 | 0.46 ± 0.09 |
 BASO (× 109/L) | 0.00 ± 0.00 | 0.00 ± 0.00 | 0.00 ± 0.00 | 0.00 ± 0.00 | 0.00 ± 0.00 | 0.00 ± 0.00 | 0.00 ± 0.00 |
 RBC (× 1012/L) | 7.85 ± 0.39 | 8.86 ± 0.26 | 8.39 ± 0.13 | 8.06 ± 0.19 | 8.49 ± 0.37 | 8.11 ± 0.22 | 8.49 ± 0.31 |
 Hb (g/dL) | 13.95 ± 0.05 | 15.77 ± 0.49* | 15.03 ± 0.19 | 14.67 ± 0.18 | 15.07 ± 0.64 | 14.67 ± 0.60 | 15.37 ± 0.52 |
 HCT (%) | 41.65 ± 0.65 | 49.23 ± 1.13* | 46.87 ± 0.99* | 45.70 ± 0.64 | 48.87 ± 1.07 | 47.90 ± 1.74 | 47.23 ± 2.14 |
 MCV (fL) | 53.25 ± 3.45 | 56.80 ± 1.24 | 55.87 ± 0.84 | 56.80 ± 1.20 | 57.67 ± 1.26 | 59.07 ± 1.32 | 55.57 ± 0.58 |
 MCH (pg) | 17.80 ± 0.80 | 17.83 ± 0.15 | 17.93 ± 0.15 | 18.20 ± 0.25 | 17.77 ± 0.17 | 18.07 ± 0.47 | 18.10 ± 0.10 |
 MCHC (g/dL) | 33.50 ± 0.60 | 31.37 ± 0.58 | 32.10 ± 0.32 | 32.10 ± 0.55 | 30.83 ± 0.65* | 30.60 ± 0.17* | 32.53 ± 0.37 |
 RDW-CV (%) | 16.85 ± 2.05 | 18.60 ± 0.40 | 19.83 ± 0.32 | 19.30 ± 0.99 | 19.27 ± 0.53 | 17.97 ± 0.58 | 18.37 ± 0.93 |
 PLT(× 109/L) | 706.0 ± 14.29 | 722.0 ± 23.18 | 808.3 ± 61.87 | 734.0 ± 26.63 | 799.7 ± 52.14 | 793.7 ± 45.95 | 855.3 ± 139.0 |
 MPV (fL) | 7.35 ± 0.15 | 8.27 ± 0.09* | 8.23 ± 0.09* | 8.20 ± 0.20* | 9.33 ± 0.19* | 8.60 ± 0.40 | 8.23 ± 0.35 |
Males | |||||||
 WBC (× 109/L) | 12.54 ± 1.69 | 10.68 ± 2.24 | 12.08 ± 2.34 | 13.74 ± 0.46 | 8.99 ± 1.07 | 11.45 ± 2.82 | 13.56 ± 3.24 |
 NEU (× 109/L) | 2.77 ± 0.56 | 3.69 ± 0.98 | 3.58 ± 1.56 | 2.32 ± 0.32 | 2.49 ± 0.61 | 2.94 ± 0.75 | 3.55 ± 0.43 |
 LYM(× 109/L) | 8.61 ± 1.70 | 5.72 ± 1.09 | 7.20 ± 0.57 | 9.69 ± 0.28 | 5.38 ± 0.97 | 7.03 ± 1.85 | 8.65 ± 3.01 |
 MONO (× 109/L) | 0.92 ± 0.29 | 0.71 ± 0.19 | 0.92 ± 0.23 | 0.91 ± 0.05 | 0.70 ± 0.15 | 0.89 ± 0.30 | 0.83 ± 0.29 |
 EOS (× 109/L) | 0.35 ± 0.03 | 0.56 ± 0.04 | 0.38 ± 0.08 | 0.67 ± 0.05 | 0.42 ± 0.10 | 0.58 ± 0.29 | 0.53 ± 0.09 |
 BASO (× 109/L) | 0.0033 ± 0.0033 | 0.00 ± 0.00 | 0.00 ± 0.00 | 0.00 ± 0.00 | 0.00 ± 0.00 | 0.00 ± 0.00 | 0.00 ± 0.00 |
 RBC (× 1012/L) | 7.66 ± 0.88 | 7.94 ± 0.59 | 8.80 ± 0.26 | 9.64 ± 0.09 | 8.76 ± 0.33 | 9.32 ± 0.54 | 9.04 ± 0.29 |
 Hb (g/dL) | 13.63 ± 1.47 | 13.40 ± 0.82 | 15.10 ± 0.44 | 16.23 ± 0.17 | 15.60 ± 0.49 | 15.83 ± 0.94 | 16.00 ± 0.46 |
 HCT (%) | 40.67 ± 4.91 | 41.73 ± 2.44 | 45.43 ± 1.34 | 49.53 ± 1.09 | 49.07 ± 1.43 | 49.50 ± 2.91 | 49.43 ± 1.62 |
 MCV (fL) | 53.03 ± 1.02 | 52.67 ± 0.90 | 51.60 ± 0.15 | 51.43 ± 1.28 | 56.07 ± 0.58 | 53.13 ± 1.59 | 54.67 ± 0.50 |
 MCH (pg) | 17.83 ± 0.15 | 16.93 ± 0.22* | 17.17 ± 0.03 | 16.87 ± 0.17* | 17.80 ± 0.12 | 16.93 ± 0.23* | 17.67 ± 0.07 |
 MCHC (g/dL) | 33.63 ± 0.68 | 32.10 ± 0.26 | 33.27 ± 0.03 | 32.80 ± 0.50 | 31.77 ± 0.18 | 32.00 ± 0.52 | 32.40 ± 0.26 |
 RDW-CV (%) | 20.80 ± 1.18 | 20.77 ± 0.57 | 20.60 ± 0.61 | 21.40 ± 0.72 | 19.30 ± 0.17 | 21.00 ± 0.91 | 21.50 ± 0.66 |
 PLT(× 109/L) | 1014 ± 220.6 | 742.0 ± 49.14 | 723.7 ± 80.05 | 751.3 ± 47.64 | 687.7 ± 70.48 | 754.3 ± 31.44 | 759.3 ± 43.84 |
 MPV (fL) | 7.03 ± 0.67 | 8.27 ± 0.18 | 7.97 ± 0.17 | 7.67 ± 0.09 | 8.67 ± 0.09 | 8.60 ± 0.40 | 8.20 ± 0.23 |