Skip to main content

Table 2 Relative organ weight of the rats treated with Aloe vera for 28 days

From: Acute and sub-acute oral toxicity of aqueous whole leaf and green rind extracts of Aloe vera in Wistar rats

Organ

Control group

A. vera whole leaf extract doses in mg/kg

A. vera green rind extract doses in mg/kg

200

400

800

200

400

800

Combined male and female

Liver

4.70 ± 0.13

4.50 ± 0.18

4.36 ± 0.17

4.48 ± 0.07

4.49 ± 0.13

4.50 ± 0.21

4.79 ± 0.22

Kidney

0.91 ± 0.04

0.88 ± 0.03

0.87 ± 0.03

0.90 ± 0.02

0.83 ± 0.02

0.84 ± 0.02

0.87 ± 0.03

Brain

0.98 ± 0.08

0.87 ± 0.07

0.93 ± 0.07

0.95 ± 0.06

0.85 ± 0.08

0.89 ± 0.07

1.07 ± 0.14

Spleen

0.59 ± 0.03

0.50 ± 0.05

0.56 ± 0.04

0.47 ± 0.04

0.41 ± 0.05**

0.47 ± 0.03

0.45 ± 0.03

Females

 Liver

4.52 ± 0.04

4.77 ± 0.11

4.61 ± 0.11

4.52 ± 0.10

4.70 ± 0.03

4.72 ± 0.36

5.11 ± 0.16

 Kidney

0.94 ± 0.07

0.89 ± 0.06

0.89 ± 0.08

0.91 ± 0.02

0.85 ± 0.00

0.86 ± 0.03

0.91 ± 0.06

 Brain

1.12 ± 0.02

0.98 ± 0.03

0.99 ± 0.13

0.96 ± 0.01

0.95 ± 0.05

0.99 ± 0.09

1.30 ± 0.15

 Spleen

0.60 ± 0.07

0.49 ± 0.02

0.55 ± 0.08

0.42 ± 0.04

0.45 ± 0.03

0.51 ± 0.01

0.40 ± 0.04

 Ovary

2.21 ± 0.44

2.63 ± 0.06

3.21 ± 0.46

1.83 ± 0.35

2.15 ± 0.54

2.01 ± 0.43

2.05 ± 0.15

Males

 Liver

4.88 ± 0.18

4.24 ± 0.20

4.12 ± 0.20

4.44 ± 0.15

4.28 ± 0.09

4.28 ± 0.19

4.46 ± 0.23

 Kidney

0.89 ± 0.05

0.87 ± 0.06

0.86 ± 0.04

0.90 ± 0.05

0.80 ± 0.04

0.82 ± 0.02

0.84 ± 0.01

 Brain

0.85 ± 0.05

0.76 ± 0.07

0.87 ± 0.07

0.94 ± 0.14

0.75 ± 0.13

0.78 ± 0.03

0.85 ± 0.00

 Spleen

0.58 ± 0.04

0.51 ± 0.13

0.58 ± 0.04

0.51 ± 0.05

0.37 ± 0.11

0.43 ± 0.03

0.49 ± 0.03

 Testis

2.76 ± 0.32

2.53 ± 0.22

2.81 ± 0.35

2.94 ± 0.33

2.69 ± 0.44

2.87 ± 0.23

2.75 ± 0.17

  1. Data are expressed as Mean ± SEM; number of rats per group, n = 4 for analysis by group and n = 3 for separate sexes analysis **significant p-value when control is compared with male and female combined