Organ | Control group | A. vera whole leaf extract doses in mg/kg | A. vera green rind extract doses in mg/kg | ||||
---|---|---|---|---|---|---|---|
200 | 400 | 800 | 200 | 400 | 800 | ||
Combined male and female | |||||||
Liver | 4.70 ± 0.13 | 4.50 ± 0.18 | 4.36 ± 0.17 | 4.48 ± 0.07 | 4.49 ± 0.13 | 4.50 ± 0.21 | 4.79 ± 0.22 |
Kidney | 0.91 ± 0.04 | 0.88 ± 0.03 | 0.87 ± 0.03 | 0.90 ± 0.02 | 0.83 ± 0.02 | 0.84 ± 0.02 | 0.87 ± 0.03 |
Brain | 0.98 ± 0.08 | 0.87 ± 0.07 | 0.93 ± 0.07 | 0.95 ± 0.06 | 0.85 ± 0.08 | 0.89 ± 0.07 | 1.07 ± 0.14 |
Spleen | 0.59 ± 0.03 | 0.50 ± 0.05 | 0.56 ± 0.04 | 0.47 ± 0.04 | 0.41 ± 0.05** | 0.47 ± 0.03 | 0.45 ± 0.03 |
Females | |||||||
 Liver | 4.52 ± 0.04 | 4.77 ± 0.11 | 4.61 ± 0.11 | 4.52 ± 0.10 | 4.70 ± 0.03 | 4.72 ± 0.36 | 5.11 ± 0.16 |
 Kidney | 0.94 ± 0.07 | 0.89 ± 0.06 | 0.89 ± 0.08 | 0.91 ± 0.02 | 0.85 ± 0.00 | 0.86 ± 0.03 | 0.91 ± 0.06 |
 Brain | 1.12 ± 0.02 | 0.98 ± 0.03 | 0.99 ± 0.13 | 0.96 ± 0.01 | 0.95 ± 0.05 | 0.99 ± 0.09 | 1.30 ± 0.15 |
 Spleen | 0.60 ± 0.07 | 0.49 ± 0.02 | 0.55 ± 0.08 | 0.42 ± 0.04 | 0.45 ± 0.03 | 0.51 ± 0.01 | 0.40 ± 0.04 |
 Ovary | 2.21 ± 0.44 | 2.63 ± 0.06 | 3.21 ± 0.46 | 1.83 ± 0.35 | 2.15 ± 0.54 | 2.01 ± 0.43 | 2.05 ± 0.15 |
Males | |||||||
 Liver | 4.88 ± 0.18 | 4.24 ± 0.20 | 4.12 ± 0.20 | 4.44 ± 0.15 | 4.28 ± 0.09 | 4.28 ± 0.19 | 4.46 ± 0.23 |
 Kidney | 0.89 ± 0.05 | 0.87 ± 0.06 | 0.86 ± 0.04 | 0.90 ± 0.05 | 0.80 ± 0.04 | 0.82 ± 0.02 | 0.84 ± 0.01 |
 Brain | 0.85 ± 0.05 | 0.76 ± 0.07 | 0.87 ± 0.07 | 0.94 ± 0.14 | 0.75 ± 0.13 | 0.78 ± 0.03 | 0.85 ± 0.00 |
 Spleen | 0.58 ± 0.04 | 0.51 ± 0.13 | 0.58 ± 0.04 | 0.51 ± 0.05 | 0.37 ± 0.11 | 0.43 ± 0.03 | 0.49 ± 0.03 |
 Testis | 2.76 ± 0.32 | 2.53 ± 0.22 | 2.81 ± 0.35 | 2.94 ± 0.33 | 2.69 ± 0.44 | 2.87 ± 0.23 | 2.75 ± 0.17 |