Fig. 7

Effect of Etpost (2 μg/ml) on time course recovery of post-ischemic changes of hemodynamic parameters, Arrhythmia score and VF incidence in the isolated rat heart. A The effect of Etpost (2 μg/ml) and Etpost+L-NAME on LVDP, data are presented as % of per-ischemia (PS) values. ^* P < 0.05 vs. IR and ^# P < 0.05 vs. Etpost (2 μg/ml); B The effect of Etpost (2 μg/ml) and Etpost+L-NAME on Post-ischemic changes of rate pressure product (RPP) in the isolated rat heart. Data are presented as % of pre-ischemia (PS) values. ^* P < 0.05 vs. IR and ^# P < 0.05 vs. Etpost (2 μg/ml). C Arrhythmia scores calculation of the reperfusion period in the isolated rat heart. The effect of IR, IPOST, IPOST+ L-NAME, Etpost (2 μg/ml), and Etpost (2 μg/ml) + L-NAME on the arrhythmia score. Scale range is (0 to 7). ^* P < 0.05 vs. IR, ^@ P < 0.05 vs. IPOST, and ^# P < 0.05 vs. Etpost; D The incidence of ventricular fibrillation (VF) calculation of the reperfusion period in the isolated rat heart. The effect of IR, IPOST, IPOST+ L-NAME, Etpost (2 μg/ml), and Etpost (2 μg/ml) + L-NAME on the incidence of VF. Data are presented as the percentage of incidence. ^* P < 0.05 vs. IR, ^@ P < 0.05 vs. IPOST and ^# P < 0.05 vs. Etpost (2 μg/ml)