Parameters | Tissues | Negative Control | Positive Control (CCl4 only) | CCl4 + 50 mg/kg b.w MP | CCl4 + 100 mg/kg b.w MP | CCl4 + 100 mg/kg b.w Silymarin | Negative Control II (Rifampicin only) | Rifampicin + 50 mg/kg b.w MP | Rifampicin + 100 mg/kg b.w MP |
---|---|---|---|---|---|---|---|---|---|
SOD (μmol/min/mg protein) | Liver | 6.14 ± 0.31a | 4.53 ± 0.22 | 4.72 ± 0.61a | 4.93 ± 0.31a | 6.20 ± 1.23a | 2.36 ± 0.19 | 2.75 ± 0.12a | 3.89 ± 0.15a |
Kidney | 3.48 ± 1.03a | 2.46 ± 0.75 | 2.61 ± 0.54a | 2.90 ± 0.44a | 3.15 ± 0.53a | 1.93 ± 0.19 | 2.76 ± 0.41a | 3.08 ± 0.26a | |
Serum | 4.29 ± 0.19a | 3.17 ± 0.10 | 3.28 ± 0.18a | 4.00 ± 0.33a | 4.34 ± 0.21a | 2.42 ± 0.07 | 2.89 ± 0.13a | 3.76 ± 0.21a | |
Catalase (μmol/min/mg protein) | Liver | 4.70 ± 0.56a | 2.89 ± 0.21 | 3.15 ± 0.11a | 4.15 ± 0.30a | 3.97 ± 1.20a | 1.63 ± 0.16 | 2.60 ± 0.41a | 3.84 ± 0.23a |
Kidney | 2.77 ± 0.15a | 2.02 ± 0.18 | 2.32 ± 0.20a | 2.47 ± 0.11a | 2.58 ± 0.20a | 1.88 ± 0.26 | 2.16 ± 0.12a | 2.53 ± 0.10a | |
Serum | 3.06 ± 0.11a | 2.38 ± 0.10 | 2.66 ± 0.14a | 2.91 ± 0.10a | 2.93 ± 0.20a | 1.76 ± 0.14 | 2.53 ± 0.20a | 3.01 ± 0.16a | |
GSH ((μmol/mg protein) | Liver | 5.77 ± 0.06a | 3.87 ± 0.01 | 4.20 ± 0.12a | 5.13 ± 0.10a | 5.43 ± 0.08a | 2.93 ± 0.08 | 3.17 ± 0.02a | 4.22 ± 0.06a |
Kidney | 3.23 ± 0.07a | 2.53 ± 0.05 | 2.88 ± 0.08a | 3.07 ± 0.09a | 3.19 ± 0.12a | 3.04 ± 0.02 | 3.15 ± 0.08a | 3.19 ± 0.10a | |
Serum | 2.66 ± 0.10a | 1.57 ± 0.22 | 2.07 ± 0.64a | 2.10 ± 0.52a | 2.49 ± 0.98a | 2.08 ± 0.02 | 2.30 ± 0.04a | 2.52 ± 0.01a |