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Table 2 Effect of 80% methanol extract of seeds of L. sativum on the level of parasitemia (expressed as mean ± SEM, n = 6)

From: Antitrypanosomal activity of hydromethanol extract of leaves of Cymbopogon citratus and seeds of Lepidium sativum: in-vivo mice model

Group of mice

Log value of parasitemia/ ml

D0

D2

D4

D6

D8

D10

D12

D14

LS-100

8.08 ± 0.08

7.98 ± 0.10

7.83 ± 0.12

7.61 ± 0.10

7.30 ± 0.08ab

7.85 ± 0.08a

8.13 ± 0.09

8.33 ± 0.04

LS-200

8.30 ± 0.08

8.33 ± 0.04

8.45 ± 0.04a

7.98 ± 0.03

7.80 ± 0.10ab

7.85 ± 0.02a

8.00 ± 0.06a

8.26 ± 0.05a

LS-400

6.90 ± 0.40

6.43 ± 0.46ab

7.36 ± 0.14

6.93 ± 0.40ab

7.43 ± 0.04ab

7.53 ± 0.02ab

7.73 ± 0.04ab

7.96 ± 0.05abc

DA-3.5

7.38 ± 0.18

7.73 ± 0.18

8.10 ± 0.18

7.93 ± 0.32

8.16 ± 0.21

8.23 ± 0.20

8.26 ± 0.21

8.53 ± 0.13

DA-28

7.80 ± 0.2

5.53 ± 0.05

5.96 ± 0.29

7.35 ± 0.14

7.46 ± 0.20

7.80 ± 0.21

8.10 ± 0.12

8.40 ± 0.10

NC

7.20 ± 0.13

7.95 ± 0.06

7.65 ± 0.20

8.17 ± 0.10

8.25 ± 0.06

8.55 ± 0.06

8.55 ± 0.06

8.70 ± 0.13

  1. D = day; D0 = the day treatment commenced; SEM = standard error of mean; LS = Lepidium sativum; NC = negative control taking 1 ml 10% DMSO; 100, 200, 400, 3.5, and 28 are doses in mg/kg; DA = Diminazene aceturate; All superscripts indicate significance at p < 0.05 (a = compared to negative control; b = compared to 3.5 mg/kg DA; c = compared to 28 mg/kg DA