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Table 1 Effect of 80% methanol extract of Cymbopogon citratus leaves on the level of parasitemia (expressed as mean ± SEM; n = 6)

From: Antitrypanosomal activity of hydromethanol extract of leaves of Cymbopogon citratus and seeds of Lepidium sativum: in-vivo mice model

Group of mice

Log value of parasitemia/ ml

D0

D2

D4

D6

D8

D10

D12

D14

CC-100

6.3 ± 0.11

7.5 ± 0.10

7.60 ± 0.13

8.0 ± 0.17

7.80 ± 0.21

7.50 ± 0.09ab

7.35 ± 0.05

7.05 ± 0.05

CC-200

7.1 ± 0.46

7.8 ± 0.40

8.20 ± 0.31

8.0 ± 0.09

7.68 ± 0.20

7.40 ± 0.10ab

7.13 ± 0.04

6.80 ± 0.05

CC-400

6.7 ± 0.42

6.83 ± 0.40a

7.93 ± 0.23

7.5 ± 0.28

6.85 ± 0.06ab

5.60 ± 0.06 abc

3.60 ± 1.13abc

1.80 ± 1.13abc

DA-3.5

7.38 ± 0.18

7.73 ± 0.18

8.10 ± 0.18

7.93 ± 0.32

8.16 ± 0.15

8.23 ± 0.20

8.26 ± 0.21

8.53 ± 0.13

DA-28

7.8 ± 0.20

5.53 ± 0.05

5.96 ± 0.29

7.35 ± 0.14

7.46 ± 0.07

7.80 ± 0.21

8.10 ± 0.12

8.40 ± 0.10

NC

7.2 ± 0.13

7.95 ± 0.06

7.65 ± 0.20

8.17 ± 0.10

8.25 ± 0.25

8.55 ± 0.06

8.55 ± 0.06

8.70 ± 0.13

  1. D = day; D0 = the day treatment commenced; SEM = standard error of mean; CC = Cymbopogon citratus; NC = negative control taking 1 ml 10% DMSO; 100, 200, 400, 3.5, and 28 are doses in mg/kg; DA = Diminazene aceturate; All superscripts indicate significance at p < 0.05 (a = compared to negative control; b = compared to 3.5 mg/kg DA; c = compared to 28 mg/kg DA
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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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