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Table 6 Effects of polyphenol rich extract of Ocimum gratissimum leaves on oxidative stress and cellular infiltration indices in cyclophosphamide-treated rats

From: Polyphenol-rich extract of Ocimum gratissimum leaves prevented toxic effects of cyclophosphamide on the kidney function of Wistar rats

Groups

Kidney SOD (μ/mg protein)

Kidney CAT (μM/mg protein)

Kidney GSH (μg/mg protein)

Kidney MDA (nM/mg protein)

Kidney H2O2 (nM/g protein)

Kidney MPO (U/mg protein)

[1] Control

2.35 ± 0.27

5.01 ± 0.35

10.04. ± 0.21

14.54 ± 0.46

24.00 ± 1.31

6.94 ± 4.05

[2] PREOG (400 mg/kg)

2.40 ± 0.03

6.08 ± 1.10

11.43 ± 0.30

16.02 ± 2.37

24.89 ± 2.30

7.09 ± 4.21

[3] CP (50 mg/kg)

1.12 ± 1.14*

2.01 ± 0.30*

5.40 ± 1.45*

30.90 ± 1.62*

40.84 ± 3.13*

35.02 ± 6.06*

[4] PREOG (400 mg/kg) + CP

2.00 ± 0.20#

4.01 ± 0.15#

9.43 ± 1.56#

18.31 ± 1.64#

29.09 ± 4.06#

16.08 ± 3.31*#

  1. Each value represents mean ± SEM (n = 7). * (p < 0.05) = significantly different from control in the same column. # (p < 0.05) = significantly different from CP (50 mg/kg) in the same column