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Fig. 9 | BMC Complementary Medicine and Therapies

Fig. 9

From: Active constituent of Polygala tenuifolia attenuates cognitive deficits by rescuing hippocampal neurogenesis in APP/PS1 transgenic mice

Fig. 9

DISS promoted the neuronal differentiation of hippocampal NSCs in APP/PS1 mice. IF analysis against NeuN was carried out to detect the mature NSCs in the hippocampus of APP/PS1 mice. (A, C and E) Representative immunostaining images of NeuN+ cells in the hippocampal CA1 (A), CA3 (C) and DG (E) regions, respectively. Scale bar = 100 μm. (B, D and F). Quantitative analysis of NeuN+ cells in the hippocampal CA1 (B), CA3 (D) and DG (F) regions, respectively. #P < 0.05; ##P < 0.01 vs. WT group; *P < 0.05 vs. APP/PS1 group. Data are represented as mean ± sem. n = 6 mice in each group; 6 slices per animal were analyzed by one-way ANOVA

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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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