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Fig. 4 | BMC Complementary Medicine and Therapies

Fig. 4

From: Active constituent of Polygala tenuifolia attenuates cognitive deficits by rescuing hippocampal neurogenesis in APP/PS1 transgenic mice

Fig. 4

The effects of the three ingredients on the migration of APP-NSCs. APP-NSCs were cultured in differentiation medium, and exposed to DISS (60 μM), OB (10 μM), and TEN (60 μM) for 7 days, respectively. The neurospheres images were captured and the migration distance of neural cells from the edge of the neurospheres were measured using by Image J software. (A) The representative micrographs of neurospheres in different group. Scale bar = 200 μm; (B) Quantitative analysis of distance of neural cells from the neurosphere. ##P < 0.01 vs. GFP-NSCs group; *P < 0.05; **P < 0.01 vs. APP-NSCs group. Data are represented as mean ± sem. This experiment was performed three times. Data were analyzed by one-way ANOVA

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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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