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Table 2 comparison of the mean anthropometric, glycemic measurement, lipid profile, and liver enzymes before and after study between two groups

From: Effect of cranberry supplementation on liver enzymes and cardiometabolic risk factors in patients with NAFLD: a randomized clinical trial

Variable

Cranberry group (n = 46)

p-value*

Placebo group (n = 48)

p-value*

p-value**

Before

After

Before

After

BMI (kg/m2)

28.17 ± 4.99

28.22 ± 5.06

0.32

28.63 ± 4.15

28.42 ± 4.07

0.68

0.34

SBP

127.39 ± 24.61

126.85 ± 25.01

0.22

124.85 ± 23.20

124.79 ± 24.25

0.89

0.37

DBP

79.35 ± 10.19

79.78 ± 10.21

0.25

77.90 ± 9.05

78.65 ± 9.32

0.07

0.62

Liver enzymes

ALT

42.74 ± 15.04

39.54 ± 16.95

0.18

47.48 ± 18.35

38.69 ± 14.20

< 0.001

0.27

AST

37.22 ± 13.51

32.98 ± 14.33

0.05

41.17 ± 16.69

31.98 ± 12.48

< 0.001

0.27

ALP

251.57 ± 32.89

224.33 ± 54.12

0.01

248.08 ± 27.18

221.40 ± 47.19

< 0.001

0.77

Lipid profile measurements

Total cholesterol

209.8 ± 64.13

189.02 ± 63.62

< 0.001

205.60 ± 50.16

200.29 ± 52.14

0.002

< 0.001

LDL-C

144.13 ± 20.62

133.96 ± 20.71

< 0.001

143.27 ± 20.02

135.17 ± 19.34

0.24

0.23

HDL-C

33.67 ± 4.21

38.28 ± 4.84

< 0.001

34.46 ± 5.00

38.0 ± 4.99

< 0.001

0.09

TG

198.9 ± 64.99

190.54 ± 65.22

< 0.001

181.50 ± 57.79

188.54 ± 66.80

< 0.001

0.01

Glycemic measurements

FBS

105.22 ± 9.04

98.65 ± 8.70

0.001

105.81 ± 9.08

100.48 ± 7.47

< 0.001

0.28

Insulin

10.38 ± 3.09

5.62 ± 2.04

< 0.001

10.65 ± 3.02

10.06 ± 2.94

< 0.001

< 0.001

HOMA-IR

2.78 ± 0.99

1.39 ± 0.62

< 0.001

2.84 ± 0.98

2.51 ± 0.85

< 0.001

< 0.001

Steatosis grade n (%)

No steatosis

0

14 (30.4)

0.04#

0

0

< 0.001#

0.001#

Grade 1

13 (28.3)

18 (39.1)

 

16 (33.3)

24 (50)

  

Grade 2

28 (60.9)

13 (28.3)

 

26 (54.2)

20 (41.7)

  

Grade 3

5 (10.9)

1 (2.2)

 

6 (12.5)

4 (8.3)

  
  1. * Within-group comparisons, P-value of paired t-test
  2. ** Between-group comparisons; p-value of ANCOVA adjusted for age, sex, and baseline values
  3. # p-value of chi-square test
  4. SBP systolic blood pressure, DBP diastolic blood pressure, LDL-C low-density lipoprotein-cholesterol, HDL-C High-density lipoprotein-cholesterol, TG triglyceride, AST alanine aminotransferase, AST aspartate aminotransferase, ALP alkaline phosphatase, FBS fasting blood sugar, HOMA-IR Homeostatic model assessment-insulin resistance