Variable | Cranberry group (n = 46) | p-value* | Placebo group (n = 48) | p-value* | p-value** | ||
---|---|---|---|---|---|---|---|
Before | After | Before | After | ||||
BMI (kg/m2) | 28.17 ± 4.99 | 28.22 ± 5.06 | 0.32 | 28.63 ± 4.15 | 28.42 ± 4.07 | 0.68 | 0.34 |
SBP | 127.39 ± 24.61 | 126.85 ± 25.01 | 0.22 | 124.85 ± 23.20 | 124.79 ± 24.25 | 0.89 | 0.37 |
DBP | 79.35 ± 10.19 | 79.78 ± 10.21 | 0.25 | 77.90 ± 9.05 | 78.65 ± 9.32 | 0.07 | 0.62 |
Liver enzymes | |||||||
ALT | 42.74 ± 15.04 | 39.54 ± 16.95 | 0.18 | 47.48 ± 18.35 | 38.69 ± 14.20 | < 0.001 | 0.27 |
AST | 37.22 ± 13.51 | 32.98 ± 14.33 | 0.05 | 41.17 ± 16.69 | 31.98 ± 12.48 | < 0.001 | 0.27 |
ALP | 251.57 ± 32.89 | 224.33 ± 54.12 | 0.01 | 248.08 ± 27.18 | 221.40 ± 47.19 | < 0.001 | 0.77 |
Lipid profile measurements | |||||||
Total cholesterol | 209.8 ± 64.13 | 189.02 ± 63.62 | < 0.001 | 205.60 ± 50.16 | 200.29 ± 52.14 | 0.002 | < 0.001 |
LDL-C | 144.13 ± 20.62 | 133.96 ± 20.71 | < 0.001 | 143.27 ± 20.02 | 135.17 ± 19.34 | 0.24 | 0.23 |
HDL-C | 33.67 ± 4.21 | 38.28 ± 4.84 | < 0.001 | 34.46 ± 5.00 | 38.0 ± 4.99 | < 0.001 | 0.09 |
TG | 198.9 ± 64.99 | 190.54 ± 65.22 | < 0.001 | 181.50 ± 57.79 | 188.54 ± 66.80 | < 0.001 | 0.01 |
Glycemic measurements | |||||||
FBS | 105.22 ± 9.04 | 98.65 ± 8.70 | 0.001 | 105.81 ± 9.08 | 100.48 ± 7.47 | < 0.001 | 0.28 |
Insulin | 10.38 ± 3.09 | 5.62 ± 2.04 | < 0.001 | 10.65 ± 3.02 | 10.06 ± 2.94 | < 0.001 | < 0.001 |
HOMA-IR | 2.78 ± 0.99 | 1.39 ± 0.62 | < 0.001 | 2.84 ± 0.98 | 2.51 ± 0.85 | < 0.001 | < 0.001 |
Steatosis grade n (%) | |||||||
No steatosis | 0 | 14 (30.4) | 0.04# | 0 | 0 | < 0.001# | 0.001# |
Grade 1 | 13 (28.3) | 18 (39.1) | 16 (33.3) | 24 (50) | |||
Grade 2 | 28 (60.9) | 13 (28.3) | 26 (54.2) | 20 (41.7) | |||
Grade 3 | 5 (10.9) | 1 (2.2) | 6 (12.5) | 4 (8.3) |