Skip to main content

Table 5 Enrichment using reactome

From: The benefit of combining curcumin, bromelain and harpagophytum to reduce inflammation in osteoarthritic synovial cells

GOID

GOTerm

Term PValue

% Associated Genes

Nr. Genes

Associated Genes Found

R-HSA:1268020

Mitochondrial protein import

0.001

6.25

4

[MTX2, PITRM1, TIMM13, TOMM70]

R-HSA:917937

Iron uptake and transport

0.009

5.17

3

[ATP6V1G1, FTH1, NEDD8]

R-HSA:9639288

Amino acids regulate mTORC1

0.008

5.45

3

[ATP6V1G1, LAMTOR5, RRAGA]

R-HSA:210991

Basigin interactions

0.001

12.00

3

[ATP1B3, BSG, SLC3A2]

R-HSA:2173782

Binding and Uptake of Ligands by Scavenger Receptors

0.000

9.52

4

[ALB, FTH1, HBA1, HSPH1]

R-HSA:447115

Interleukin-12 family signaling

0.009

5.26

3

[CDC42, PSME2, SOD2]

R-HSA:8950505

Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation

0.003

7.89

3

[CDC42, PSME2, SOD2]

R-HSA:9020591

Interleukin-12 signaling

0.005

6.38

3

[CDC42, PSME2, SOD2]

R-HSA:1442490

Collagen degradation

0.012

4.69

3

[COL6A1, COL6A3, CTSL]

R-HSA:1474290

Collagen formation

0.005

4.44

4

[CD151, COL6A1, COL6A3, CTSL]

R-HSA:186797

Signaling by PDGF

0.009

5.17

3

[COL6A1, COL6A3, THBS1]

R-HSA:2022090

Assembly of collagen fibrils and other multimeric structures

0.001

6.56

4

[CD151, COL6A1, COL6A3, CTSL]

R-HSA:216083

Integrin cell surface interactions

0.004

4.71

4

[BSG, COL6A1, COL6A3, THBS1]

R-HSA:1632852

Macroautophagy

0.001

4.41

6

[LAMTOR5, RRAGA, SQSTM1, TOMM70, TUBA1A, TUBB1]

R-HSA:2995410

Nuclear Envelope (NE) Reassembly

0.019

4.00

3

[BANF1, TUBA1A, TUBB1]

R-HSA:389957

Prefoldin mediated transfer of substrate to CCT/TriC

0.001

10.71

3

[CCT4, TUBA1A, TUBB1]

R-HSA:389958

Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding

0.002

9.38

3

[CCT4, TUBA1A, TUBB1]

R-HSA:389960

Formation of tubulin folding intermediates by CCT/TriC

0.001

12.00

3

[CCT4, TUBA1A, TUBB1]

R-HSA:5626467

RHO GTPases activate IQGAPs

0.002

9.38

3

[CDC42, TUBA1A, TUBB1]

R-HSA:8852276

The role of GTSE1 in G2/M progression after G2 checkpoint

0.000

6.49

5

[MAPRE1, PSMD6, PSME2, TUBA1A, TUBB1]

R-HSA:9663891

Selective autophagy

0.003

4.94

4

[SQSTM1, TOMM70, TUBA1A, TUBB1]