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Fig. 4 | BMC Complementary Medicine and Therapies

Fig. 4

From: The benefit of combining curcumin, bromelain and harpagophytum to reduce inflammation in osteoarthritic synovial cells

Fig. 4

LPS induces gene expression and release in medium of catabolism, inflammation and pain markers. Human synovial cells were treated with LPS (1 μg/ml) for 24 h. A - At the end of the experiments, RNA was extracted. Relative mRNA expression of MMP-1, MMP-3, MMP-13, NGF and IL-6 was determined by RT-PCR. Values are compared to untreated cells and presented as a log Fold Change (compared to the control group). B - Culture media were collected and ELISA was performed to assayed MMP, IL-6 and PGE2 concentration in medium. Values are expressed as μg/ml medium (n = 4). *: p-value< 0.05, **: p-value< 0.01, ***: p-value< 0.001

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