Table 4 Protein ligand interaction detail of VEGFR with isolated compounds
Samples | Docking Score | Interaction details | |||||||
|---|---|---|---|---|---|---|---|---|---|
Ligand | Number/position of atom | Receptor | Name of amino acid (residue) | Number of amino acid | Interaction | Distance (Ã…) | Energy (kcal/mol) | ||
PH-1 | -5.9865 | O | 10 | N | ASP | 1046 | H-acceptor | 3.11 | -0.8 |
O | 9 | HZ3 | LYS | 868 | H-acceptor | 2.7 | -0.5 | ||
PH-2 | -5.7853 | O | 7 | O | ASP | 1046 | H-donor | 2.72 | -1.8 |
O | 7 | HZ3 | LYS | 868 | H-acceptor | 2.6 | -1.5 | ||