Fig. 4
The serum levels of IL-1β and TNF-α of the adjuvant-induced arthritis (AIA) rats were quantified using ELISA. Petroleum ether extract of LF (PEL) treatment significantly reduced the production of IL-1β and TNF-α in the serum of AIA rats, and its efficacy was superior to that of ethyl acetate extract of LF (EEL) and water extract of LF (WEL). Data were recorded as mean ± SEM. Differences were assessed by Dunnett’s multiple comparisons test and one-way ANOVA, ***P < 0.001 vs MC, ****P < 0.0001 vs MC. (n = 6)