Fig. 5
Effect of CISCFE on MMP-3, MMP-9 and TIMP-1 mRNA levels in A549 cells, MRC-5 cells and BLM-treated rats. Effect of CISCFE MMP-3 (A), MMP-9 (B) and TIMP-1 (C) mRNA levels in A549 and MRC-5 cells was observed. The influence of the CISCFE on MMP-3 (D), MMP-9 (E) and TIMP-1 (F) mRNA levels in BLM-treated rats was noted. The results are presented as the means ± SD. (n = 6). aa, P < 0.01 vs the control group; b, P < 0.05 and bb, P < 0.01 vs the Wnt-1 group. ##, P < 0.01 vs the normal group; *, P < 0.05 and **, P < 0.01 vs the model group