Skip to main content

Table 2 IC50, CC50 and SI values of fractions and subfractions of A. heterophyllus leaves dichloromethane extracts

From: An in vitro study of an Artocarpus heterophyllus substance as a hepatitis C antiviral and its combination with current anti-HCV drugs

Sample IC50 (μg/mL) CC50 (μg/mL) Selectivity Index
Fraction FR1 > 100 > 1000 > 10
FR2 48.27 ± 8.82 > 1000 (1008.27 ± 28.23) > 20.72
FR3 3.79 ± 2.35 > 100 (193.77 ± 9.40) > 26.39
FR4 4.60 ± 1.46 > 100 (191.28 ± 0.02) > 21.76
Subfraction FR3T1 6.15 ± 0.60 > 50 (94.28 ± 8.44) > 8.13
FR3T2 < 3.12 > 25 (31.90 ± 5.34) > 8.01
FR3T3 4.69 ± 0.95 > 100 (130.14 ± 27.92) > 21.32
FR3T4 42.03 ± 2.92 > 200 (251.21 ± 1.75) > 4.76
FR3T5 6.84 ± 1.15 > 25 (38.76 ± 0.07) > 3.65
FR3T6 30.42 ± 1.23 > 400 (417.38 ± 77.23) > 13.15
FR3T7 2.39 ± 0.34 > 12.5 (16.16 ± 9.75) > 5.23
  1. The experiment was performed in triplicate