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Table 2 IC50, CC50 and SI values of fractions and subfractions of A. heterophyllus leaves dichloromethane extracts

From: An in vitro study of an Artocarpus heterophyllus substance as a hepatitis C antiviral and its combination with current anti-HCV drugs

Sample

IC50 (μg/mL)

CC50 (μg/mL)

Selectivity Index

Fraction

FR1

> 100

> 1000

> 10

FR2

48.27 ± 8.82

> 1000 (1008.27 ± 28.23)

> 20.72

FR3

3.79 ± 2.35

> 100 (193.77 ± 9.40)

> 26.39

FR4

4.60 ± 1.46

> 100 (191.28 ± 0.02)

> 21.76

Subfraction

FR3T1

6.15 ± 0.60

> 50 (94.28 ± 8.44)

> 8.13

FR3T2

< 3.12

> 25 (31.90 ± 5.34)

> 8.01

FR3T3

4.69 ± 0.95

> 100 (130.14 ± 27.92)

> 21.32

FR3T4

42.03 ± 2.92

> 200 (251.21 ± 1.75)

> 4.76

FR3T5

6.84 ± 1.15

> 25 (38.76 ± 0.07)

> 3.65

FR3T6

30.42 ± 1.23

> 400 (417.38 ± 77.23)

> 13.15

FR3T7

2.39 ± 0.34

> 12.5 (16.16 ± 9.75)

> 5.23

  1. The experiment was performed in triplicate