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Table 4 Inhibitory activities of three extracts of H. zeyheri on the expression of cytokines (TNF-α, IL10) and cell viability in human U937 macrophages at 50 μg/mL concentration

From: In vitro antioxidant activity of crude extracts of Harpagophytum zeyheri and their anti-inflammatory and cytotoxicity activity compared with diclofenac

Extract

TNF-α (pg/mL)

IL-10 (pg/mL)

Cell viability (%)

Ethyl acetate

47.92 ± 0.69a

7.95 ± 0.05a

98.96 ± 2.16a

Ethanol

164.07 ± 0.74b

8.63 ± 0.37a

99.27 ± 4.02a

Water

217.13 ± 3.24c

8.06 ± 0.48a

99.97 ± 2.48a

Diclofenac

44.49 ± 6.62a

8.42 ± 0.30a

25.11 ± 1.24b

Quercetin

73.06 ± 1.94d

31.55 ± 2.69b

49.48 ± 5.51c

  1. Values with different superscript letters in each column are significantly different at p < 0.05