Fig. 1From: In vitro inhibitory effect of obtusofolin on the activity of CYP3A4, 2C9, and 2E1The activity of eight major CYP isoforms in the presence of obtusofolin or positive inhibitors. All CYP isoforms were inhibited by their positive inhibitors. Obtusofolin significantly inhibited the activity of CYP3A4, 2C9, and 2E1. *P < 0.05 relative the negative controlsBack to article page